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Wei-Hsuan Hsu Selected Research

monascin

1/2015Monascus secondary metabolites monascin and ankaflavin inhibit activation of RBL-2H3 cells.
7/2014A novel PPARgamma agonist monascin's potential application in diabetes prevention.
6/2014Monascin attenuates oxidative stress-mediated lung inflammation via peroxisome proliferator-activated receptor-gamma (PPAR-γ) and nuclear factor-erythroid 2 related factor 2 (Nrf-2) modulation.
2/2014Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice.
12/2013Monacolin K and monascin attenuated pancreas impairment and hyperglycemia induced by advanced glycation endproducts in BALB/c mice.
11/2013A novel natural Nrf2 activator with PPARγ-agonist (monascin) attenuates the toxicity of methylglyoxal and hyperglycemia.
7/2013Peroxisome proliferator-activated receptor-γ activators monascin and rosiglitazone attenuate carboxymethyllysine-induced fibrosis in hepatic stellate cells through regulating the oxidative stress pathway but independent of the receptor for advanced glycation end products signaling.
6/2013Monascin improves diabetes and dyslipidemia by regulating PPARγ and inhibiting lipogenesis in fructose-rich diet-induced C57BL/6 mice.
2/2013Effects of monascin on anti-inflammation mediated by Nrf2 activation in advanced glycation end product-treated THP-1 monocytes and methylglyoxal-treated wistar rats.
5/2012Monascus-fermented metabolite monascin suppresses inflammation via PPAR-γ regulation and JNK inactivation in THP-1 monocytes.
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Wei-Hsuan Hsu Research Topics

Disease

12Hyperglycemia
08/2021 - 12/2012
10Inflammation (Inflammations)
07/2014 - 05/2012
9Insulin Resistance
07/2014 - 05/2011
8Neoplasms (Cancer)
08/2021 - 06/2010
4Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2021 - 03/2013
4Carcinogenesis
01/2018 - 06/2010
4Mouth Neoplasms (Oral Cancer)
01/2018 - 12/2010
3Hyperlipidemias (Hyperlipidemia)
08/2021 - 06/2013
3Obesity
06/2021 - 03/2013
2Hyperplasia
10/2021 - 11/2012
2Hypersensitivity (Allergy)
10/2021 - 01/2015
2Fibrosis (Cirrhosis)
12/2013 - 07/2013
2Type 2 Diabetes Mellitus (MODY)
11/2013 - 02/2013
2Hyperinsulinism (Hyperinsulinemia)
07/2013 - 06/2013
2Dyslipidemias (Dyslipidemia)
06/2013 - 03/2013
1Atopic Dermatitis (Atopic Eczema)
10/2021
1Weight Loss (Weight Reduction)
10/2021
1Body Weight (Weight, Body)
08/2021
1Dysbiosis
08/2021
1Cardiovascular Diseases (Cardiovascular Disease)
07/2021
1Weight Gain
06/2021
1Mitochondrial Diseases (Mitochondrial Disease)
04/2018
1Carcinoma (Carcinomatosis)
01/2017
1Neoplasm Metastasis (Metastasis)
01/2017
1Ovarian Neoplasms (Ovarian Cancer)
01/2017
1Cardiac Arrhythmias (Arrythmia)
12/2016
1Hemorrhage
06/2016
1Atrial Fibrillation
06/2016
1Squamous Cell Carcinoma of Head and Neck
12/2015
1Asthma (Bronchial Asthma)
01/2015
1Hypercholesterolemia
07/2014
1Pneumonia (Pneumonitis)
06/2014

Drug/Important Bio-Agent (IBA)

12monascinIBA
01/2015 - 10/2011
7Advanced Glycation End ProductsIBA
07/2014 - 12/2012
7Peroxisome Proliferator-Activated Receptors (PPAR)IBA
06/2014 - 10/2011
6ankaflavinIBA
01/2015 - 02/2012
6Pyruvaldehyde (Methylglyoxal)IBA
07/2014 - 12/2012
5Ethanol (Ethyl Alcohol)IBA
12/2012 - 06/2010
4PPAR gammaIBA
07/2014 - 06/2013
4Insulin (Novolin)FDA Link
07/2014 - 05/2011
4N(6)-carboxymethyllysine (carboxymethyllysine)IBA
07/2014 - 07/2013
4Receptor for Advanced Glycation End ProductsIBA
12/2013 - 02/2013
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2013 - 05/2011
4AntioxidantsIBA
03/2013 - 01/2012
3CytokinesIBA
10/2021 - 06/2010
3Polysaccharides (Glycans)IBA
08/2021 - 05/2011
3ProstaglandinsIBA
12/2015 - 06/2010
3Rosiglitazone (Avandia)FDA Link
06/2014 - 07/2013
3Blood Glucose (Blood Sugar)IBA
12/2013 - 12/2012
3Reactive Oxygen Species (Oxygen Radicals)IBA
07/2013 - 06/2010
3Glucose (Dextrose)FDA LinkGeneric
07/2013 - 01/2012
3EnzymesIBA
03/2013 - 01/2012
2ResveratrolIBA
06/2021 - 12/2013
2cordycepinIBA
01/2018 - 01/2017
2anthraceneIBA
01/2018 - 12/2015
2OvalbuminIBA
01/2015 - 05/2012
2dimerumic acidIBA
12/2013 - 07/2013
2Lovastatin (Mevacor)FDA LinkGeneric
12/2013 - 02/2012
2LigandsIBA
07/2013 - 02/2013
2Pioglitazone (Actos)FDA Link
06/2013 - 10/2011
22-chloro-5-nitrobenzanilideIBA
06/2013 - 10/2011
2FructoseIBA
06/2013 - 01/2012
2Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2011 - 06/2010
2benz(a)anthracene (benzanthracene)IBA
06/2011 - 06/2010
1fucoidanIBA
10/2021
1Interleukin-22 (IL-22)IBA
10/2021
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2021
1Therapeutic UsesIBA
10/2021
1Sucrose (Saccharose)IBA
08/2021
1bisphenol AIBA
06/2021
1Butyrates (Butyrate)IBA
06/2021
1EstersIBA
06/2021
1LipidsIBA
06/2021
1Galactose (Galactopyranose)FDA LinkGeneric
04/2018
1Proteins (Proteins, Gene)FDA Link
04/2018
1ZincIBA
04/2018
1Free RadicalsIBA
04/2018
1Proliferating Cell Nuclear Antigen (PCNA)IBA
01/2018
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2018
1Liver ExtractsIBA
01/2018
1Estrogens (Estrogen)FDA Link
01/2017
1CalciumIBA
12/2016
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
12/2016
1Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
12/2016
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
12/2016
1Angiotensin IIIBA
12/2016
1Serine (L-Serine)FDA Link
12/2016
1AnticoagulantsIBA
06/2016
1ThrombinFDA Link
06/2016
1DabigatranFDA Link
06/2016
1Pharmaceutical PreparationsIBA
12/2015
1pardaxinIBA
12/2015
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
06/2014
1PPAR alphaIBA
06/2014
1Transcription Factors (Transcription Factor)IBA
06/2014
1Oleic Acid (Oleate)IBA
02/2014

Therapy/Procedure

2Therapeutics
07/2021 - 01/2017
1Drug Therapy (Chemotherapy)
11/2021
1Immunomodulation
10/2021
1Adjuvant Chemotherapy
12/2015